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Mephedrone (4-Methylmethcathinone, 4-MMC, C₁₁H₁₅NO) is a synthetic cathinone from the phenethylamine family. In controlled laboratory settings, Mephedrone is studied for its effects on monoamine transporter activity — specifically serotonin, norepinephrine, and dopamine reuptake inhibition. It is a close structural relative of methcathinone with a methyl group at the 4-position of the phenyl ring.
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| Attribute | Details |
|---|---|
| Product Name | Mephedrone (4-Methylmethcathinone / 4-MMC) |
| Chemical Formula | C₁₁H₁₅NO |
| Molecular Weight | 177.24 g/mol |
| Purity | ≥99% (GC/MS and HPLC verified) |
| Appearance | White to off-white crystalline powder |
| CAS Number | 1189805-46-6 (Mephedrone) |
| Legal Status | Schedule I (US) / Controlled in most countries |
| Intended Use | In vitro and laboratory research only |
| Storage | 20°C–25°C (room temperature), 2–3 year stability |
| Shipping | Standard 3–5 days / Overnight available |
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Mephedrone (4-MMC) is studied in controlled laboratory research for its effects on:
- Serotonin Reuptake — How Mephedrone interacts with serotonin transporters (SERT)
- Dopamine Reuptake — Effects on dopamine transporters (DAT)
- Norepinephrine Reuptake — Effects on norepinephrine transporters (NET)
- Monoamine Transporter Activity — Combined SERT/DAT/NET inhibition profile
- Pharmacokinetics — Absorption, distribution, metabolism, and excretion
- Toxicology — Safety profiles and dose-response relationships
- Structure-Activity Relationships — How cathinone structure affects potency vs methcathinone
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⚠️ Hazard Warnings
- 🔴 SCHEDULE I CONTROLLED SUBSTANCE — Mephedrone is illegal in most countries without proper research authorization.
- 🔴 EXTREME ABUSE POTENTIAL — Mephedrone is one of the most addictive synthetic cathinones. Even a single use can lead to dependence.
- 🔴 CARDIOVASCULAR RISK — May cause tachycardia, hypertension, arrhythmia, myocardial infarction, and sudden cardiac death.
- 🔴 SEROTONIN SYNDROME RISK — Can cause life-threatening serotonin syndrome when combined with SSRIs, MAOIs, or other serotonergic drugs.
- 🔴 HYPERTHERMIA RISK — Can cause dangerous elevation of body temperature (>40°C / 104°F).
- 🔴 NEUROTOXICITY — Prolonged exposure causes permanent damage to serotonin and dopamine neurons.
- 🔴 DO NOT COMBINE — Never mix with alcohol, opioids, benzodiazepines, MAOIs, or other CNS depressants.
- 🔴 KEEP AWAY FROM CHILDREN — Even microgram doses can be fatal to children.
🚨 First Aid Instructions
- IF OVERDOSE IS SUSPECTED: Call 911 IMMEDIATELY. Symptoms include extreme agitation, rapid heart rate, seizures, hyperthermia, chest pain, and loss of consciousness. Administer naloxone if opioids are also involved.
- IF BREATHING STOPS: Call 911. Begin CPR if trained. Do NOT wait for emergency services.
- IF SEIZURES OCCUR: Clear area of hard objects. Do NOT restrain. Place on side. Call 911.
- IF SKIN CONTACT OCCURS: Wash skin with soap and water immediately. Remove contaminated clothing.
- IF IN EYES: Rinse eyes thoroughly with water for five minutes. Remove contact lenses, if possible.
- IF INGESTED (accidental): Call Poison Control (1-800-222-1222) immediately. Do NOT induce vomiting.
- IF HYPERTHERMIA OCCURS: Move to cool area. Apply cold compresses. Call 911 — body temperature above 104°F (40°C) can be fatal.
- IF SEROTONIN SYNDROME OCCURS: Call 911 IMMEDIATELY — this is life-threatening. Symptoms include confusion, rapid heart rate, high blood pressure, dilated pupils, muscle twitching, and high fever.
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Mephedrone (4-MMC) is used in pharmacological research, toxicology, neuroscience, and receptor binding studies (serotonin reuptake, dopamine reuptake, norepinephrine reuptake, pharmacokinetics) under controlled laboratory conditions. It is NOT for human consumption.
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Mephedrone (4-MMC) is a Schedule I controlled substance in the US and regulated in most countries. It is legal for in vitro research with proper credentials from an authorized institution.
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What is the difference between Mephedrone and Methylone?
Mephedrone (4-MMC) has a methyl group at the 4-position of the phenyl ring, while Methylone (3,4-methylenedioxy-N-methylcathinone) has a methylenedioxy ring. Mephedrone is more potent at the serotonin transporter, while Methylone has stronger dopamine activity.
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Mephedrone (4-methylmethcathinone) is the name of this powerful chemical compound. It is available in different names, such as meow meow, mephedrone, 4-methoxymethcathinone, 4-methyl methcathinone, and 4-MMC.
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Mephedrone is a synthetic stimulant that differs from methamphetamine in many ways. Mephedrone and Methamphetamine are both dopamine and serotonin releasers. The compounds differ in their main active metabolites. Methamphetamines are methamphetamine and 4-methyl methcathinone. Mephedrone is an enantiomer and does not include any amphetamine. NEP and Mephedrone are also less powerful hallucinogens than methamphetamine or hexylone. They are not as strong as a base hallucinogen.
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